"4ÆM" was first debuted last night at the 2020 Game Awards as part of the announcement for the Cyperpunk 2077 game soundtrack.
The new offering follows on from earlier Miss Anthropocene singles "My Name is Dark", "So Heavy I Fell Through The Earth", and "Violence".
Miss Anthropocene will be Grimes' first album since 2015's Art Angels.
Last month Grimes and Zola Jesus had a lengthy discussion on Twitter about AI and the future of music.
"4ÆM" is out now. Grimes' Miss Anthropocene album arrives via 4AD on 21 February 2020, and is available to pre-order now.