"Let Me Go" is RY X's first feature since releasing "Oceans" with Ólafur Arnalds in January.
It also marks Duke Dumont's first new release since last month's "Love Song".
The cinematic track will feature on DUALITY alongside "Love Song", as well as earlier singles "Therapy" and "Ocean Drive".
DUALITY will also include collaborations with How To Dress Well, Zak Abel, Roland Clark, Say Lou Lou, and more.
"Let Me Go" featuring RY X is out now on Virgin EMI / Universal. Duke Dumont's DUALITY album is due for release on 17 April.