The uknowhatimsayin¿ rapper will host iFruit Radio, which will appear in the game after the new update on 12 December.
Brown will host the show alongside Skepta. The radio station will include tracks by slowthai, JME, Travis Scott, Freddie Gibbs and Madlib, J Hus, D Double E, Headie One, Koffee, ScHoolboy Q, Essie Gang, and many others.
iFruit Radio will also include a new track by Baauer and Channel Tres, featuring Danny Brown, called "Ready To Go".
Previous celebrity hosts in the Grand Theft Auto V universe include Frank Ocean and Vegyn, Big Boy, Kenny Loggins, Cara Delevingne, Gilles Peterson, Twin Shadow, Flying Lotus, The Alchemist and Oh No.
Frank Ocean recently unveiled a new collaboration with Skepta titled "Little Demon".