Bring Me The Horizon will be headlining the Victoria Park multi-weekend extravaganza on 31 May 2019.
The artists joining them on the same day include Run The Jewels, Nothing But Thieves, IDLES, Scarlxrd and Yonaka - more names are to be added soon.
Yesterday the London festival revealed Christine and the Queens as another headliner, alongside announcing Metronomy, Toro Y Moi, and more for the same day.
Elsewhere the festival will see performances from Bon Iver, Mac DeMarco, Little Dragon, The Chemical Brothers, Little Simz, and many more.